This work focused on a novel approach to enhance the quality of phosphate ore with medium-low grade and high silicon content. The proposed method involved a series of steps including nitric acid leaching, separation, and re-precipitation. The work focused on investigating the nitric acid leaching process and the precipitation of the leaching solution, resulting in an impressive P2O5 recovery rate of 99.92%. The phosphorus present in the leaching solution was re-precipitated as phosphate through two stages of mineralization using calcium carbonate slurry (CaCO3) and lime slurry (CaO) respectively. The work conducted a comprehensive analysis on the impact of various factors such as pH, reaction time, stirring speed, and temperature on the recovery of P2O5. The findings from Taguchi experiment and analysis of variance (ANOVA) revealed that the pH and temperature of the reaction had the most significant influence on P2O5 recovery. Based on the results, the optimal parameters for the first mineralization stage were determined. In the subsequent second mineralization stage, the P2O5 recovery reached 99.54% within an acidic pH. The precipitated product was identified as calcium hydrogen phosphate dihydrate, exhibiting a P2O5 grade of 39.65% in the overall enrichment process.